(Cincinnati, Ohio-AP) -- Reggie Sanders, Kenny Lofton and Jason Kendall homered in succession as the Pittsburgh Pirates beat Cincinnati 10-to-1 Monday and ruined the Reds' first game at Great American Ball Park. Ken Griffey Junior'd double was the first hit in the long-awaited park. But every other moment belonged to the Pirates.

Sanders, a member of the Reds' 1995 playoff team, hit a two-run homer off Jimmy Haynes that started a second-inning rally. Haynes walked counterpart Kris Benson before giving up a three-homer homer to Lofton, followed by Kendall's shot five pitches later. The Reds have been outscored 18-3 while losing two exhibitions to Cleveland and the regular-season opener.

Benson gave up three hits and three walks in six and one-third innings to win his first opening-day start. Pokey Reese's error at second helped the Reds load the bases in the third, and Benson walked Austin Kearns to force in Cincinnati's lone run.