Los Angeles, CA -- (Sports Network) - Fifth-seeded Russian Marat Safin and sixth-seeded American Mardy Fish advanced, while second-seeded Spaniard Fernando Verdasco fell in Wednesday's second-round action at the $475,000 Countrywide Classic tennis event.

Frenchman Florent Serra upset Verdasco in 6-2, 7-6 (7-4) fashion on the hardcourts at the Los Angeles Tennis Center.

Fish looked like he might have been heading for the same upset fate after dropping the first set of his match in a tiebreak. But he dropped just one game over the final two sets to earn a 6-7 (5-7), 6-1, 6-0 victory over fellow countryman Vincent Spadea.

Safin, however, had little trouble in dispatching American Wayne Odesnik 6-3, 6-2.

But another Day-3 upset did come when German Denis Gremelmayr upended fourth- seeded Spaniard Feliciano Lopez 7-5, 7-5 in just under two hours.

This week's top seed is American star Andy Roddick, who will open his stay here against Serbian lucky-loser Dusan Vemic in the second round on Thursday.

The 2008 Countrywide winner will collect $79,000.